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Information × Registration Number 0223U000082, 0121U111938 , R & D reports Title Investigation of adsorption properties and in vitro behavior of biocomposites based on biogenic hydroxyapatite modified by magnetite and chitosan popup.stage_title Head Synytsia Anna О., Registration Date 03-01-2023 Organization Institute of Problems of Materials Science named after IM Frantsevich of the National Academy of Sciences of Ukraine popup.description2 The purpose of the work is to study the patterns of formation of the structure and properties of biogenic hydroxyapatite/magnetite/chitosan composite materials depending on the type and amount of magnetite introduced into their composition, to study the phase composition, structure, adsorption properties and in vitro behavior of the obtained materials. The sorption capacity of previously synthesized composite materials based on biogenic hydroxyapatite modified with magnetite (1, 5, 25, 50% by weight of the composition) and chitosan was investigated, which affects not only the storage, but also the adsorption properties of the composites. In vitro experiments were carried out on the rate of resorption of the obtained materials, which is confirmed by a change in pH, loss of mass and a decrease in the size of the particles of the materials. In addition, during experiments on Madin-Darby calf kidney cells and Madin-Darby dog kidney cells, no cytotoxic effect was detected for all composite materials, regardless of the ratio of components and the method of magnetite synthesis. Product Description popup.authors Otychenko Oksana M. popup.nrat_date 2023-01-03 Close