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Registration Number

0223U000522, 0122U001200 , R & D reports

Title

Studying the physical aspects of dual-energy X-ray absorptiometry for the diagnosis of osteoporosis and obesity at the early stages of the disease

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Head

Krech Anton V., Кандидат технічних наук
Opolonin Oleksandr D., Кандидат фізико-математичних наук

Registration Date

10-01-2023

Organization

Institute for scintillation materials NAS Ukraine

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In the paper, an analysis of literature data on the medical use of dual-energy X-ray absorptiometry (DХA or DEXA) was carried out, the main modes of operation of DRA scanners of various modifications were determined. A methodology for model calculations of signals of scintillator-photodiode-type scintillator detectors has been developed. An Excel database has been prepared for model calculations (X-ray spectra, mass attenuation coefficients, etc.). The spectra of X-ray radiation for the energy range 20 keV - 150 keV, which passed through a biological object consisting of fat, soft and bone tissues, were calculated. A comparison of different methods of determining the mineral density of bone tissue against the background of muscle tissue was carried out, the main factors affecting the accuracy of DRA were analyzed (scattered radiation, X-ray pulsations, quantization noise, error of matching two images, etc.). Using radiographic images of fragments of domestic birds, obtained in three energy ranges (20 50 keV, 50-100 keV, 60-150 keV), the feasibility of using the model calculations proposed in the work was confirmed.

Product Description

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Karavaeva Natalya L.
Kretch Anton V.
Makhota Serhiy V.
Opolonin Oleksandr D.

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2023-01-10