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Information × Registration Number 0223U000833, 0122U001269 , R & D reports Title Development of novel means of medical diagnostics by biomedical nanotechnologies and modern ultrasonic and fluorescence methods popup.stage_title Head Horbenko Halyna P., д.ф.-м.н. Registration Date 20-01-2023 Organization V.N. Karazin Kharkiv National University popup.description2  Physical models to interpret the effect of additional annealing on the form, intensity, and dynamics of radiation in a broad band of radiation in the UV region of wavelengths associated with exciton decay were developed. It was shown that additionally annealing affects the luminescent broad spectral band associated with the radiative relaxation of self-trapped exciton. The attainable spatial resolution in the process of plane-wave ultrasound probing from different angles was estimated on the basis of the previously developed theory of the Doppler response formation. In the theoretical calculations coherent compounding of the Doppler response signals was conducted over the period of changing the steering angles of probing. An analytical expression for the ultrasound system sensitivity function over the field, which corresponds to the point spread function,was obtained. It was observed that in the case of a rectangular weighting window for the response signals, the resolution is determined by the well-known sinc-function. It was found that the magnitude of the lateral resolution is inversely proportional to the range of the steering angles. A comprehensive study of the interaction of the antiviral drugs tilorone, molnupiravir, and amantadine with the receptor-binding domain of the SARS CoV-2 spike protein, angiotensin-converting enzyme 2, and proteins was performed. It was found that it is most energetically favorable for tilorone to form complexes with angiotensin-converting enzyme 2, while molnupiravir interacts also with the receptor-binding domain of the SARS CoV-2 spike protein. Product Description popup.authors Tarabara Uliana К. Barannyk Evgen O. Vus Kateryna O Girnyk Serhii A. Zhitnyakivska Olga А. Trusova Valeriya M. Sheina Iryna V. popup.nrat_date 2023-01-20 Close