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Information × Registration Number 0223U001477, 0118U003377 , R & D reports Title Physical effects and mechanisms of interactions of biological molecules and supramolecular biological systems with nanoparticles and nanostructured media. popup.stage_title Head Dovbeshko Halyna I., Registration Date 28-01-2023 Organization Institute of Physics of National Academy of Sciences of Ukraine popup.description2 The physical effects and mechanisms of interaction of bioorganic molecules (nucleotide bases - adenine, thymine, lipids - dioleoylphosphatidylcholine, phosphatidylserine, sphingomyelin, cholesterol, etc.), biological macromolecules - proteins of lysozyme, albumin, oligonucleotides, nucleic acids and supramolecular nanoscale biological systems (biological membranes, lipid aggregates) were studied , protein complexes, living cells) with nanoparticles - MoS2, WS2, BN, graphene oxide and nanostructured media of different nature (carbonic, metallic, organic, mineral, combined) in order to identify patterns of such interactions. The methods of experimental spectroscopic research and microscopic research (contrast increase by 10 times, staining without dyes) have been improved thanks to new equipment and mathematical processing, and a number of spectroscopic markers have been developed for membranes of different composition, mitochondria, synaptosomes, brain tissues. New computational algorithms and data analysis methods for their in silico study are proposed. Product Description popup.authors Yesylevskyy Semen Oleksandrovych Andreev O Yevgen leksandrovych Barabash Yurii M. Boyko Vitaliy Volodymyrovuch Hanulia Taras Oleksandrovych Gnayuk Olena P Dovbeshko Galyna Ivanivna Lebedieva Tetiana Oliksiivna Olenchuk Maryna Volodymyrivna Polovyi Ivan Oleksandrovych Fedorov Volodymyr Olegovych popup.nrat_date 2023-01-28 Close