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Information × Registration Number 0223U001592, 0118U005171 , R & D reports Title Affinity sensor system based on "smart" hybrid nanocomplexes for determination of specific nucleic acid sequences. Section 2. Development of "smart" hybrid nanocomplexes popup.stage_title Head Dziadevych Serhii V., Доктор біологічних наук Registration Date 31-01-2023 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description2  It was found that the drop in photoluminescence (PL) in solutions containing AgInS2/ZnS quantum dots (QDs) and gold nanoparticles (NPs) modified with short MP-SH and SH-DP oligonucleotides, respectively, occurred regardless of the presence of long complementary to short oligonucleotide sequences 80-bcr-abl. Electrolytic aggregation of NPs in solutions does not affect PL QDs. However, in the presence of both types of oligonucleotide-modified nanoparticles, the PL QDs falls during the first day, and eventually leads to complete PL quenching. Such dynamics of interaction between QDs and NPs occurs only under the condition of their modification with oligonucleotides. Product Description popup.authors Kucherenko Daria Yu. Nesterenko Yevheniya О. Sergeyeva Tetyana A. Soldatkin Oleksandr O Shkotova Liudmyla V popup.nrat_date 2023-01-31 Close