Search academic texts

Information × Registration Number 0223U001766, 0121U000020 , R & D reports Title To determine the risk factors for the formation of cognitive dysfunction in patients with chronic obstructive pulmonary disease in combination with coronary heart disease popup.stage_title Head Serik Serhiy , Доктор медичних наук Registration Date 03-02-2023 Organization Government Institution "L.T.Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine" popup.description2 122 patients were examined according to the research topic. Among them, 46 patients with COPD and concomitant coronary heart disease, 38 patients with isolated COPD, 26 patients with isolated coronary heart disease, and 12 patients of the control group. All patients underwent a general clinical examination, which included: collection of complaints, history, objective examination, anthropometric measurements - height, weight, calculation of body mass index, data collection using MMRC, СAT, Borg questionnaires. A 6-minute walk test, a study of the function of external breathing, pulse oximetry, and somnography were conducted. The hospital Anxiety and Depression Scale (HADS), the test for the presence of generalized anxiety disorder (GAD-7), the Montreal Cognitive Assessment (MoCA). It has been established that patients with COPD, both with and without coronary heart disease, have moderate cognitive impairment and a moderate degree of anxiety. The most significant predictor of cognitive dysfunction in patients with COPD with coronary heart disease was the increase in airway obstruction. Ethylmethylhydroxypyridine succinate in the complex therapy of COPD and coronary heart disease contributed to the reduction of cognitive impairment and anxiety. Implementation of the results will improve the effectiveness of forecasting, prevention and treatment of cognitive disorders in comorbid pathology.  Product Description popup.authors Antonova Inna V. Gridasova Liudmyla M. Kolesnikova Olena Mykolaivna Kostiuk Olena Samokhina Lyubov Tokareva A. Y. Tsedrik Ludmyla A. Chenchik Tetyana popup.nrat_date 2023-02-03 Close