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Information × Registration Number 0223U001771, 0119U003663 , R & D reports Title Determination of regularities of formation of antibiotic resistance of persistent clinical isolates of microorganisms and of ways of its minimization in patients with leukemia popup.stage_title Head Rybalska Alla P, Registration Date 03-02-2023 Organization State Institution "Institute of Hematology and Transfusiology of the National Academy of Medical Sciences of Ukraine" popup.description2  Object: 52 patients with leukemia, 30 persons of the control group, 14 persons of the comparison group; 496 strains of microorganisms, 60 antibiotic drugs, 6 antimycotics. Methods: hematological, microbiological, statistical. Research on the formation of antibiotic resistance of microbial pathogens in patients with leukemia, which are included in three priority categories according to WHO data, is presented. Bioindication of the main biotopes and regulation of the composition of the microbiota with the help of accompanying therapy with probiotic preparations containing natural associants contributed to timely diagnosis, prevention or minimization of infectious and inflammatory complications in patients with leukemia. A method of restoring the sensitivity of conditionally pathogenic microorganisms to antibacterial drugs has been developed. Medical and social effect. Medicine. Product Description popup.authors Goryainova Nаdiia V Kyselova Olena A Mel'nyk Olena A Nemyrovska Liudmyla M Rybalska Alla P Skachkova Nadiia K popup.nrat_date 2023-02-03 Close