Search academic texts

Information × Registration Number 0223U002823, 0120U100646 , R & D reports Title To develop and to investigate the efficacy of new endocrine disease prevention tools for clinical implementation popup.stage_title Head Kravchenko Viktor I., д.мед.н. Registration Date 09-03-2023 Organization State Institute "V.P. Komissarenko Institute Of Endocrinology And Metabolism of The National Academy of Medical Science of Ukraine" popup.description2 Daily urine samples were obtained from 263 selected respondents aged 18-69 years. The median iodine excretion by its concentration was 75.17 μg/l, the 1st and 3rd percentiles were 47.47 and 115.5 μg/l, respectively. In another study, 55 patients with nodular goiter and 125 people without thyroid pathology from the northern region of Ukraine were examined. Insufficient intake of iodine in the body among residents of the region was established. A decrease in the content of iron, copper, zinc and selenium in the blood serum was observed in nodular pathology of the thyroid gland (thyroid gland), which significantly increased the risk of VZ. In order to study elemental support in autoimmune thyroiditis (AIT), 119 residents of the northern region of Ukraine were examined: of them, 32 with diagnosed latent AIT were the experimental group and 87 without thyroid pathology were the control group. In the study of iodine excretion with urine, the median ioduria in the control group was 72.5 μg/l, in the experimental group among patients with AIT 52.6 μg/l, which indicated insufficient intake of iodine in the body and the presence of mild iodine deficiency. Decreased levels of magnesium, zinc, and copper were found in examined patients with AIT. Studies were also carried out in the case of newly detected diffuse toxic goiter of moderate severity, Graves' disease (CH), 104 patients and 37 people without thyroid pathology were examined. In Graves' disease, a reduced level of selenium in the blood was observed, which correlated with a significantly increased titer of antibodies to the thyroid-stimulating hormone (TSH) receptor. 102 patients were included in the study of vitamin D supply to patients with Graves' disease and the general population, of which 60 had moderate CKD. The control group included 42 individuals without thyroid pathology. With HCG, 20% of patients had an obvious deficiency, 50% - deficiency, 28.85% - inadequate supply and only 1% - normal supply. Product Description popup.authors Grishakova Tetyana Kovtun Volodymyr Krasnikov Volodymyr Luzanchuk Igor A Rakov Oleg Simurov Oleksiy popup.nrat_date 2023-03-09 Close