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Information × Registration Number 0224U002927, 0123U102891 , R & D reports Title Synthesis of model particulate air pollutants (PM) based on silicon dioxide and graphene and development of countermeasures using newly synthesized chelators and sorbents based on functionalized nanoparticles for binding polluting heavy metals and pharmaceuticals popup.stage_title Head Sotnik Svitlana O., к.х.н. Registration Date 15-03-2024 Organization L. V. Pisarzhevskii Institute Of Physical Chemistry of The National Academy of Sciences of Ukraine popup.description2   Two types of the model pollutants: carbon-based particles obtained by pyrolysis of organic precursors or electrochemical exfoliation of graphite electrodes, and porous and non-porous silicon dioxide particles of different sizes were objects of the investigation. The purpose of the work was to obtain models of natural toxic pollutants and to study their permeability and effect on the nerve terminals of the brain. Transmission and scanning electron microscopy, atomic force spectroscopy, dynamic light scattering method, Raman and IR spectroscopy, elemental (CHN) analysis, X-ray diffraction method, low-temperature nitrogen adsorption, cyclic voltammetry and preparatory electrolysis at controlled potential were used in the work. It was established that the sample of the graphene doped with nitrogen, as well as the sample of mesoporous silica obtained in the work, do not show neurotoxicity in relation to the nerve terminals of the brain. At the time of the beginning of the research work, there was no information in the literature about graphene materials that are non-toxic to the nerve terminals of the brain. The materials obtained in the work can be used as safe non-toxic carriers for the delivery of active components of medicines into the cell or as sorbents of toxic substances. The results of the work can be used in the field of biology and medicine. The work is important for the development and introduction of new safe materials in the field of nano-neurotechnology, biotechnology and medicine. Product Description popup.authors Pariiska Olena O. popup.nrat_date 2024-03-15 Close