Registration Number
0224U031533,
(0122U000784)
, R & D reports
Title
The mechanisms of MXene interactions with biological systems
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Дослідження механізмів взаємодії системи «MXene-мікроорганізм» та «MXene-соматична клітина»
Head
Pohorelov Maksym V., Доктор медичних наук
Registration Date
09-05-2024
Organization
Sumy State University
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to establish the general regularities of interaction of MXene with biological systems depending on the chemical composition and structure of nanolaminates
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We have made an important breakthrough in the development of new biomaterials by investigating the toxicity and properties of MXene Nb4C3 nanomaterials. It was found that these nanomaterials are not toxic to various cells, including mesenchymal stem cells, at concentrations up to 10 μg/ml. This opens the way for their use in medicine and biotechnology.
A unique aspect of this research is the creation of a polymer three-dimensional nanofiber membrane with MXene, which is not only biocompatible but also conductive. It has shown high efficiency in degradation and water absorption, especially after treatment with oxygen plasma. These membranes proved to be an excellent environment for cell growth and development, which is important for regenerative medicine.
The use of fluorescent microscopy demonstrated that cells thrive and grow well on these membranes, forming healthy and active structures. However, an important discovery was that these materials do not possess antibacterial properties, indicating the need for additional research in this direction. Overall, the results show promising prospects for MXene materials in the development of modern biomedical technologies.
Product Description
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Pohorielov Maksym V.
Roshchupkin Anton A.
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2024-05-09
