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Registration Number

0224U032802, (0116U007550) , R & D reports

Title

Study of biocompatibility of degradable metal alloys with different composition.

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Визначення біосумісності металевиих сплавів у результаті підшкірної імплантації лабораторним тваринам.

Head

Погорєлов Максим Володимирович,

Registration Date

05-12-2024

Organization

Sumy State University

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 Object of research: processes of integration of implants. The purpose of the work is to determine the features of the integration of coated implants in cell culture and in the tissues of model rats. The subject of the study is the peculiarities of the integration of implants with biocoatings. Research methods: cell cultures, raster electron microscopy, biomechanical methods, morphometry In the early days after the implantation of metal structures made of bioinert alloys, adhesion of the organic matrix occurs on their surface, while the presence of a hydroxyapatite coating ensures more stable adhesion and a polymorphic cellular composition, which is a predictor of direct osseointegration. The presence of stimulation of the proliferation of osteoblasts compared to fibroblasts indicates a possible osteoinductive effect of the hydroxyapatite coating.

Product Description

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Deineka Volodymyr M.
Oleshko Oleksandr M.
Pohorielov Maksym V.

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2024-12-05