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Information × Registration Number 0225U001725, (0122U000385) , R & D reports Title Investigation of regularities of structure and properties formation of biocomposites for medical purpose popup.stage_title Дослідження закономірностей формування структури та властивостей біокомпозитів медичного призначення Head Sych Olena Ye., к.т.н. Registration Date 05-02-2025 Organization Frantsevich Institute for Problems of Materials Science National Academy of Science of Ukraine popup.description1 The purpose of the research work is investigation of regularities of structure and properties formation of new biocomposites for medical purposes, in which the basic components are hydroxyapatite and/or carbon nanostructured materials, as well as the development of techniques for emission spectral, mass spectrometric, atomic absorption and physicochemical methods for analysis of the obtained materials. popup.description2 The work has been carried out in the field of biomedical materials science and is focused on composite materials based on biogenic hydroxyapatite for medical purposes. It has been established that modification of CVD bioceramics with oxygraphene increases the resorption rate by 4 times and increases the compressive strength by 30%, which, in combination with adsorption properties and absence of cytotoxicity, makes it promising for replacing defects in cancellous bone tissue in orthopedics and traumatology. It has been shown that the technological conditions for obtaining composites based on hydroxyapatite glass ceramics and carbon fibers allow preserving the nanostructure of the fibers, and the heat treatment of hydrate cellulose in the presence of 2-4 % polymethylxyloxane allows obtaining a carbon fiber silicon-containing composite with antibacterial properties, which makes it promising for the manufacture of medical textiles. It has been shown that during the interaction of biogenic hydroxyapatite/magnetite/chitosan composites with saline under static conditions, the process of resorption (dissolution) occurs most intensively in the first 2 days, followed by a gradual slowdown and stabilization on day 15-16. The composites do not exhibit cytotoxic effects, which, in combination with other properties, makes them promising for replacing unloaded bone areas in combination with targeted drug delivery and magnetotherapy. The materials are recommended for further medical and laboratory research as promising materials for medical use. Product Description popup.authors Serhieiev Volodymyr P. Sych Olena Ye. Boshytska Nataliia V. Pinchuk Nataliia D. Tomyla Tamara V. Kononko Iryna V. Babutina Tetiana Ye. Klipov Valery D Protsenko Liudmyla S. Romanenko Olha M. Zenkov Vitalii S. Kononko Nataliia V. Kondratenko Iryna H. Sepitaia Valentyna V. Riabchenko Liubov M. Synytsia Anna О. Bykov Oleksandr I. Olifan Olena I. Yevych Yan I. Hohotsi Yelena H. Parkhomei Oleksandr R. Harbuz Viktor V. Silinska Tetiana A. Budylina Olha M. Mediukh Vira K. Petrova Vira A. Kuzmenko Liudmyla M. Terentieva Tetiana M. Kurochkin Volodymyr D. Romanova Larysa O. Kaushan Valentyna V Vira A. Sydorenchuk popup.nrat_date 2025-02-05 Close