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Information × Registration Number 0225U003691, (0122U001962) , R & D reports Title Natural biomolecules and their analogues are the basis for creating molecular ensembles to solve problems of chemistry, medicine and agrochemistry popup.stage_title Властивості оксигено-вмісних та нітрогено-вмісних природних сполук, їх функціоналізованих похідних та ізостерних аналогів. Head Khylia Volodymyr P., Доктор хімічних наук Registration Date 01-08-2025 Organization Taras Shevchenko National University of Kyiv popup.description1 Design and development of optimal preparative methods for the synthesis of natural bioheterocycles and their synthetic derivatives - oxygen-containing and nitrogen-containing natural compounds and alkaloids (flavones, isoflavones, 3-aryl coumarins, 4-aryl coumarins, 3-aryliso-coumarins) furocoumarins, pyranocoumarins, isoxazoles, pyrazoles, azepinones, pyrimidines, (iso) quinolines), terpenoids, spirocyclic compounds and their isostere analogues, including sulfonyl halides, fluoro-, phosphorus-containing and amino acid derivatives. popup.description2 The project is aimed at solving both fundamental problems of modern organic chemistry and practical tasks, in particular, at creating new reagents for organic chemistry, functional materials, and broad-spectrum drugs. The aim of the work is to design and develop optimal preparative methods for the synthesis of natural bioheterocycles and their synthetic derivatives - oxygen-containing and nitrogen-containing natural compounds and alkaloids (flavones, isoflavones, 3-arylcoumarins, 4-arylcoumarins, 3-arylisocoumarins, 4-arylisocoumarins, dihydro(iso)coumarins, furocoumarins, pyranocoumarins, isoxazoles, pyrazoles, azepinones, pyrimidines, (iso)quinolines), terpenoids, spirocyclic compounds and their isosteric analogues, including sulfonyl halides, fluoro-, phosphorus-containing and amino acid derivatives. The development of new methods for the synthesis of natural and synthetic biomolecules will involve the use of accessible and environmentally friendly starting reagents, focused on the functionalization of the obtained products; Preference will be given to synthesis methods based on the cost-effectiveness and environmental friendliness of the process. Conducting comprehensive studies to establish the basic patterns of physicochemical, spectral and biological properties will be useful for the needs of the pharmaceutical industry, materials science and agriculture.  Product Description popup.authors Blahun Oleksandr P. Veselskiy Stanislav P. Hlibov Yevhen K. Hryhorenko Oleksandr О. Zhersh Serhii A. Moskvina Viktoriia S. Shablykina Olha V. Schokol Tetiana V. Shtanova Lidiya Ya. popup.nrat_date 2025-08-01 Close