Registration Number
0225U003815,
(0125U003149)
, R & D reports
Title
Determination of wound healing and anti-inflammatory activity of plant extract samples from Scots pine needles
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Визначення ранозагоювальної та протизапальної активності зразків рослинних екстрактів з хвої сосни звичайної
Head
Tsisak Alona O., Кандидат біологічних наук
Registration Date
26-08-2025
Organization
Odesa I.I. Mechnikov National University
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Determination of wound healing and anti-inflammatory activity of extracts from Scots pine needles by conducting experimental pharmacological studies aimed at substantiating the prospects for their further use
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The anti-inflammatory and wound-healing activity of the studied samples of extracts from Scots pine needles was evaluated. In the linear cut wound model, it was found that the use of extracts contributes to a significant reduction in the length of the wound and its healing time, exceeding the effectiveness of the standard comparison drug (Levomekol). The most pronounced reparative effect was demonstrated by Sample 2, which reduced the healing time by 50% compared to the control. In the trypsin inflammation model in rats, all samples showed anti-exudative activity, which was confirmed by a significant decrease in the increase in the volume of the affected limbs. The highest effect was found in Sample 2 (88.86% at 24 hours), which exceeded the effectiveness of ibuprofen. The practical value of the results lies in substantiating the possibility of creating new anti-inflammatory and reparative agents based on plant extracts, which are characterized by high efficiency and potential for clinical use.
Product Description
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Tsisak Alona O.
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2025-08-26
