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Information × Registration Number 0226U000226, (0124U002412) , R & D reports Title Development of criteria for assessing the safety of raw cow's milk based on the content of 17β-estradiol popup.stage_title Розроблення критеріїв оцінки безпечності молока-сировини коров’ячого за вмістом 17β-естрадіолу Head Kukhtyn Mykola D., Доктор ветеринарних наук Registration Date 06-01-2026 Organization Ternopil Research Station Institute of Veterinary Medicine of the National Academy of Agrarian Sciences of Ukraine popup.description1 To determine the content of 17ß-estradiol in the milk of cows under different physiological conditions and to develop a methodology for determining and criteria for evaluating the maximum permissible concentration of this hormone in raw milk when it is accepted for processing popup.description2 The maximum permissible concentration of 17ß-estradiol in raw milk when accepted for processing is substantiated, not more than 500 pg/cm3. ​Methodological recommendations "Criteria for assessing the safety of raw cow's milk by the content of 17β-estradiol". ​Final report. It was found that if the content of 17ß -estradiol in raw milk is from 20.0 to 2500 pg/cm3, there is no effect on the infusoria. ​With the content of 17ß -estradiol in milk within 5000.0–5500.0 pg/cm3, a more pronounced toxic effect on the cultures of infusoria Tetrachymena pyriformis is manifested during cultivation for 96 hours, against 24 hours of incubation. The process of milk separation affects the distribution of 17ß -estradiol between cream and skim milk. ​The amount of 17ß -estradiol in skim milk was almost 5-7 times less than in cream. ​Under the pasteurization mode 85.0 ± 1.0 ° C for 1 min. and during boiling for 5 min. the amount of 17ß -estradiol in milk decreases, on average, by 5%. ​During the storage of butter at -18 ° C for 9 months, the amount of 17ß -estradiol is reduced to 25%, and at a temperature of -9 ° C to 20%. ​Consumers: milk processing enterprises of various forms of ownership in Ukraine. Product Description popup.authors Mykola D. Kukhtyn Ohrym Svetlana Antonivna Chernyshenko Olena Y. Kryvokhyzha Yevgen M. Tykhonova Bohdana Ye. Pepko Volodymyr O. Tetiana S. Trukhanovych popup.nrat_date 2026-01-06 Close