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Information × Registration Number 0226U000966, (0125U000433) , R & D reports Title Synthesis of new crownophanes with a diphenylcoumaranocoumarone fragment and the study of their interaction with various substrates to form supramolecular complexes for the creation of new materials. popup.stage_title Розробка методу синтезу краунофанів з одним чи двома фрагментами кумаранокумарону. Вивчення впливу розчинників, співвідношення реагентів і каталізатора та температури на час і вихід продуктів реакції. Head Kyrychenko Tetiana I., Доктор хімічних наук Registration Date 19-01-2026 Organization Physico-Chemical Institute O. Bogatsky National Academy of Sciences of Ukraine popup.description1 Development of effective methods for the synthesis of new crownophanes with one or two diphenylcoumaronocoumarone fragments. Investigation of the processes of complex formation of synthesized macrocyclic compounds with guest molecules. popup.description2 The object of research – Method for the synthesis of crownophanes with one or two diphenylcoumaroncoumarone fragments. The aim of this work – Development of a convenient method for the synthesis of new crownophanes with a diphenylcoumaroncoumarone fragment. Heating benzyl and resorcinol in a mixture of acetic, hydrochloric acids, and chloroform at 62 °C for 48 hours yielded the starting dihydroxyphenylcoumaron. Several methods for the synthesis of crown ethers with coumaranocoumarone moieties have been tested. It was found that the best method is to boil dihydroxyphenylcoumarancoumarone with polyethylene glycol ditosylates for 35 hours in the benzene/50% aqueous NAOH solution system in the presence of an interfacial transfer catalyst – BuNI. The product yield was 71.6%. Replacing benzene with toluene slightly increases the yield (73%), but requires the addition of an additional amount of catalyst due to its partial decomposition, which affects the purity of the isolated product. Carrying out the reaction by traditional methods by boiling the reagents at higher temperatures in n-butanol or DMF in the presence of potassium carbonate affects the purity of the product, although the yield of the crude product is higher. Product Description popup.authors Tetiana I. Kyrychenko Kulyhina Kateryna Yu. Bohashchenko Tetiana Yu. Yakovenko Iryna S. popup.nrat_date 2026-01-19 Close