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Information × Registration Number 0226U000967, (0124U000326) , R & D reports Title Effect of magnetic field and laser radiation on interfraction rearrangement of hemoglobin molecules popup.stage_title Дослідження впливу змінного магнітного поля на процеси міжфракціїної перебудови молекул гемоглобіну під впливом лазерного випромінювання Head Mamilov Serhii O., Кандидат фізико-математичних наук Registration Date 19-01-2026 Organization V.G. Baryakhtar Institute of Magnetism of the National Academy of Sciences of Ukraine (IMag NAS of Ukraine) popup.description1 The purpose of the work is to study the dynamics of the processes of transformation of hemoglobin forms in peripheral tissues under the combined influence of external laser irradiation and a magnetic field and to establish the configuration and parameters of the magnetic field, which will allow controlling the fractional transitions of hemoglobin molecules popup.description2 The aim of the work is to study the dynamics of the transformation processes of hemoglobin forms in peripheral tissues under the combined influence of external laser irradiation and a magnetic field and to establish the configuration and parameters of the magnetic field, which will allow to control the inter-fractional transitions of hemoglobin molecules. A specialized experimental stand has been created to study the combined effect of an alternating magnetic field and laser irradiation on the processes of interfractional transitions of hemoglobin molecules. The magnetic field frequency range is 20 Hz–1000 Hz. Using hybrid quantum mechanical/molecular mechanical modeling, it has been shown that in the α-subunit of hemoglobin, there is a stronger hydrogen bond between the oxygen molecule and distal histidine, which significantly affects the optical properties of hemoglobin. Solvation causes a significant red shift in the Sorre band of the α- and β-subunits and in the Q-bands of the β-subunit. It has been shown that the simultaneous exposure to low-intensity laser radiation and a constant magnetic field of 50 mT gives the maximum effect (up to an 18% increase) at radiation powers corresponding to a photon flux of about 5•1016 photons per second, which allows for more flexible control of the intermolecular rearrangement of hemoglobin complexes. Product Description popup.authors Veligosckiy Dmitro V. Saliuk Olha Yu. Skirta Uyriy B. Орел Ірина Валеріївна Sharai Iryna V. Ostapenko Oleksandra S. Olexij S. Svitaylo popup.nrat_date 2026-01-19 Close