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Information × Registration Number 0226U002796, (0123U101563) , R & D reports Title Scientific substantiation of improved technologies of anesthetic support and intensive therapy for wounded servicemen popup.stage_title Теоретичні та експериментальні дослідження Head Khytryi Hryhorii P., Доктор медичних наук Registration Date 06-03-2026 Organization Ukrainian Military Medical Academy popup.description1 To substantiate and optimize anesthesia provision and intensive therapy for wounded servicemen to improve treatment outcomes popup.description2 The study is devoted to the analysis of the results of our own clinical observations and scientific research aimed at improving anesthetic support and intensive care of wounded servicemen with severe hemorrhagic shock within the framework of the Damage Control Resuscitation (DCR) concept. The work was carried out on the basis of medical institutions of the military medicine system and covers various stages of medical care - from advanced surgical groups to specialized hospitals. The study analyzed the clinical course of traumatic illness in wounded with massive blood loss, the features of the development of hemorrhagic shock and trauma-induced coagulopathy, as well as their influence on the choice of anesthetic support methods and intensive care tactics. Special attention is paid to the role of the anesthesiologist as a key member of the DCR multidisciplinary team, responsible for maintaining adequate perfusion, minimizing secondary injuries and optimizing conditions for surgical control of bleeding. The paper presents a comparative analysis of various strategies of infusion and transfusion therapy, including restrictive resuscitation, the use of blood components in physiological ratios, early correction of hypocalcemia and coagulopathy, and the use of vasopressor support in patients with unstable hemodynamics. The impact of the selected anesthetic tactics on the indicators of systemic hemodynamics, metabolic status, and the course of the postoperative period was analyzed. The results obtained indicate that the integration of DCR principles into anesthetic support algorithms allows reducing the volume of non-physiological infusion, reducing the severity of metabolic disorders, and stabilizing hemodynamics in the most critical period of treatment. It was established that the choice of anesthetics and anesthesia methods in wounded patients with hemorrhagic shock should be based not only on the depth of anesthesia, but also on their effect on systemic vascular tone. Product Description popup.authors Oleksii V. Tkhorevskyi Yurii D. Ukhach Volodymyr M. Moshkivskyi Tetiana V. Levchenko Oleksandr V. Raboshchuk popup.nrat_date 2026-03-06 Close