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Information × Registration Number 0303U001401, 0100U002731 , R & D reports Title Studying of a pathogenetic bases at myelodysplastic syndrome. popup.stage_title Вивчення проліферативної активності та оцінка апоптозу кровотворних клітин хворих на різні форми МДС з вивченням морфофункціонального стану гемопоетичних клітин. Head Issakova L.M., Registration Date 27-02-2003 Organization Kiev Research Institute of Haematolojy and Blood Transfusion popup.description2 Object of research: patients on MDS, cells of the PB and BM, serum and plasma of blood. Methods are used: common hematological, cytochromical, common immunological, immunophenotyping and electronic microscopy. It is established: substantial growth of frequency morphological defective neutrophilic granulocytes of the PB at ill all forms MDS; the most common early structural attribute apoptosis of hematopoietic cells of BM at patients MDS is them dissociation associates stromal and hemopoietic elements; a high level apoptosis an index neutrophilic granulocytes and lymphocytes of the PB at all variants MDS; a various level expressive antigene CD95 + and proliferative activity hemopoietic cells depending on variant MDS; significant decrease of bactericidal function of neutrophiles; decrease of activity SDH in lymphocytes of the PB and BM and in erythroid elements of BM. Medicine.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close