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Information × Registration Number 0305U003169, 0104U003633 , R & D reports Title To study the influence of ionizing radiation on changes of brain interhemispheric asymmetry as a cerebral base of psychopathology in the remote period after Chernobyl accident popup.stage_title Розробка протоколу визначення домінантної півкулі головного мозку, право- та ліворукості, уніфікованої діагностики психічних розладів. Визначення ефектів опромінення у дозах більше 1 Зв на зміни міжпівкульної асиметрії. Head Loganovsky Konstantin Nikolaevich, Registration Date 23-02-2005 Organization Research Centre for Radiation Medicine popup.description2 Object of study: 60 сlean-up workers with mental disorders, irradiated in doses over 1 Sv; 20 not irradiated patients with mental disorders; 10 practically healthy persons. Purpose of study - to develop a protocol of determination of dominant hemisphere of cerebrum, right- and left-handed, unified diagnostic of mental disorders. To reveal effects of ionizing radiating in doses over 1 Sv on hemisphere asymmetry changes. Methods of study - clinical neurological and psychiatric, neuropsychological, psychodiagnostical, neurophysiological, statistical. It was designed and approved protocol of determination of dominant hemisphere of cerebrum, right- and left-handed, and unified diagnostic of mental disorders and diseases of nervous system; structure of database. Neuropsychological by the particularity of organic mental disorders beside persons, irradiated in doses over 1 Sv was a reduction of function activity of dominant hemisphere of cerebrum and compensatory raising of function of nondominant hemisphere.Neuropsychological markers of ionizing radiating in doses 1-5 Sv was verify. There were revealed particularities of neurofunctional breaking in doses over 1 Sv and asymmetry of cerebral hemodynamics. Neuropsichyatric effects are concluded in increase an negative psychopatological symptomatic, increase relative delta-power, in fronto-temporal area particularly, and reducing absolute teta-power in temporal area of left hemisphere, diffusive reducing of alpha-power. The conception of cerebrum radiosensitivity and primary damage localization in cortico-limbic system of dominant (left) hemisphere was proved. Product Description popup.authors popup.nrat_date 2020-04-02 Close