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Information × Registration Number 0307U001681, 0106U001583 , R & D reports Title The erythrocyte antioxidant system and heme oxygenase activiny in different ratorgans under hemolytic agent actson popup.stage_title Дослідження впливу гемолітичних агентів на антиоксидантну системі еритроцитів і гемоксигеназну активність різних органів щурів Head Kaliman P.A., Registration Date 19-04-2007 Organization Kharkov national university named after V.N. Karazin popup.description2 The aim of this study was to investigate the both erythrocyte antioxidant system and heme oxygenase activity in rat heart, vessels and lung under hemolytic anemia caused by cadmium chloride or phenylhydrazine. Subject of this investigation was heme metabolism and some parameters of antioxidant-prooxidant status of rat's heart, vessels, lung and blood serum under hemolytic anemia. The Wistar rats were used in the work. The development of cadmium hemolytic anemia was shown to accompanied by the heme oxygenase induction and the activation of free radical processes in rat heart, vessels and lung. It can be conditioned by the heme entering to the cells of these organs from bloodstream. The increasing of heme oxygenase activity under phenylhydrazine hemolytic anemia can be caused by both the activation of free radical oxidation in rat heart and vessels owing to hypoxia, and the heme content products accumulation in rat lung. Product Description popup.authors popup.nrat_date 2020-04-02 Close