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Information × Registration Number 0307U001687, 0106U001581 , R & D reports Title The effect of alimentary factors - modulators of reactive oxygen and nitrogen species level on the biomembrane function under aging popup.stage_title Прооксидантно-антиоксидантний баланс та структурно-функціональний стан біомембран призастосуванні незбалансованих дієт Head Nikitchenko U., Кандидат технічних наук Registration Date 23-02-2009 Organization Kharkov national university named after V.N. Karazin popup.description2 The objects of study were liver microsomal, mitochondrial and postmitochondrial fractions, erythrocytes and plasma of blood of Wistar rats. The state of prooxidant-antioxidant balance under unbalanced by proteins and vitamins content nutrition and calorie restricted diet (CRD), g-irradiation and nutritional addition from Aronia melanocarpa was investigated. It was established, that under CRD glutathione peroxidase activity was significantly increased and under unbalanced feeding ration antioxidant enzymes activities were decreased. Lipid hydroperoxides content in blood plasma, mitochondria and microsomes of rat liver had significantly increased in response to unbalanced diet. Prooxidant-antioxidant balance changes in response to g-irradiation were shown to be more expressed in rats with unbalanced feeding ration. Introduction of nutritional addition from Aronia melanocarpa to unbalanced ration had normalized lipid peroxidation products content in investigated tissues and had no essential effect on thestate of antioxidant defence. Product Description popup.authors popup.nrat_date 2020-04-02 Close