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Information × Registration Number 0308U003917, 0106U002340 , R & D reports Title Studying of neural grafting in correction of experimental cognitive decline in rats popup.stage_title Вивчити ефективність нейротрансплантації в корекції експериментального когнітивного дефіциту у щурів Head Tsymbaliuk Vitaliy I., Registration Date 21-07-2008 Organization National Medical University by Bogomolets popup.description2 Transient global brain ischemia, produced by 20 min 4 vessel occlusion,results in cognitive decline in operated animals, persisting for 10-12 months. Registration of field potentials reveals stable decrease in long-term potentiation of synaptic transmission. This allows considering the model as relevant for studying the correction of cognitive deficits. Stereotactic grafiting of cell suspension of CA1 zone of E18-19 foetal rat brain provides for partial restoration of a range of behavioral tests parameters and long-term potentiation of synaptic transmission, lasting for 9-12 month post grafting. Product Description popup.authors popup.nrat_date 2020-04-02 Close