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0408U002316,
к.мед.н.
22-04-2008
o
Anti-atherogenic effect of cryopreserved placenta at experimental atherosclerosis
Kondakov Igor Igorevych,
popup.head Yurchenko Tatyana Mycolaevna
popup.opponent Шепітько Володимир Іванович
popup.opponent Петренко Олександр Юрійович
Дисертаційна робота присвячена вивченню антиатерогенних ефектів кріоконсервованої плаценти при експериментальному атеросклерозі. Показано, що введення алогенної кріоконсервованої плаценти кроликам з експериментальним атеросклерозом на першому тижні призводило до нормалізації ліпідного обміну, вірогідного підвищення рівня естрадиолу в сироватці крові. На 3-й тиждень після введення АКП кількість "ліпіднавантажених" лейкоцитів у периферичній крові наближувалась до контрольних показників, вірогідно знижувалась площа ураження аорти без стадії атерокальцинозу. Через 6 тижнів, введення АКП викликало неоваскуляризацію міокарда й видновлювало структурно-функціональну цілісність судинного ендотелію аорти.
2008-04-22
2020-04-04
Updated: 2025-12-08
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