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0413U000342,
к.мед.н.
17-01-2013
o
Age-related changes proangiogenic activity of endothelium in patients with hypertension and its correction.
Parasyuk Elena,
popup.head Lishnevskaya V.Y.
popup.opponent Боднар Петро Миколайович
popup.opponent Малиновська Ірина Едмундівна
Дисертацію присвячено вивченню проангіогенної активності ендотелію у хворих на ГХ похилого віку та її зв'язку з NO-синтезуючою активністю ендотелію. В роботі було показано, що, оскільки у людей похилого віку, хворих на гіпертонічну хворобу, проангіогенна активність ендотелію залежить від функціонального стану ендотелію, а саме NO-синтезуючої активності, для підвищення синтезу фактора росту ендотелію судин необхідно застосовувати препарати з ендотеліопротекторним ефектом (периндоприл). Показано, що додавання L-аргініну до терапії периндоприлом покращує функціональний стан ендотелію шляхом надавання субстрату для синтезу оксиду азоту та підвищує рівень фактора росту ендотелію судин.
2013-01-17
2020-04-04
Updated: 2025-12-07
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