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Information × Registration Number 2119U004390, Article popup.category Thesis Title popup.author popup.publication 01-01-2019 popup.source_user Сумський державний університет popup.source https://essuir.sumdu.edu.ua/handle/123456789/80872 popup.publisher Sumy State University Description It is known that endothelial dysfunction plays a leading role in the pathogenesis of vascular brain disorders. One of the driving factors that contributes to the development of endothelial dysfunction is a potent endogenous vasoconstrictor ‒ endothelin-1, which exerts its effects through interaction with a specific type A receptor. Given that smoking is an important risk factor for endothelial disorders and stroke, the relevance of its study is undeniable. popup.nrat_date 2025-05-12 Close