Реєстраційний номер
2124U012904, Матеріали видань та локальних репозитаріїв
Категорія
Текст
Назва роботи
The burdened medical history of the mothers-in-partum – risks for the newborn
Автор
Horlenko Olesya
Chukhran Jurij
Kossey Gabriella
Ivano Viktoriia
Sochka Nataliia
Symulyk Volodymyr
Горленко Олеся Михайлівна
Чурхан Юрій Юрійович
Коссей Габріелла Барнабашівна
Іваньо Вікторія Володимирівна
Сочка Наталія Володимирівна
Симулик Володимир Дмитрович
Horlenko Olesya
Chukhran Jurij
Kossey Gabriella
Ivano Viktoriia
Sochka Nataliia
Symulyk Volodymyr
Horlenko Olesya Mykhailivna
Churkhan Yurii Yuriiovych
Kossei Habriella Barnabashivna
Ivano Viktoriya Volodymyrivna
Sochka Nataliya Volodymyrivna
Symulyk Volodymyr Dmytrovych
Дата публікації
01-10-2024
Постачальник інформації
Ужгородський національний університет
Першоджерело
https://dspace.uzhnu.edu.ua/jspui/handle/lib/68962
Видання
Aluna Publishing
Опис
Aim: To improve early diagnosis in the mothers-in-partum, with a burdened of medical case history, taking into account the pathological pattern «mothernewborn» analysis
Materials and Methods: Two groups of mothers-in-partum (n=109) with burdened anamnesis were analyzed, in comparison with mothers of children
with control group date(n=31).
Results: As for the course of pregnancy, there was a predominance of values of chronic Fetoplacental insuffieciency data (33,91±2,16 vs. 12,92±2,36%,
p<0,001), Preeclampsia (38,54±1,67 vs. 22,67±2,48 %, p<0,001) in comparation with control group date. Regarding the course of labour, deliveries by
Cesarean section were the most frequent among mothers in the first group in comparison with the data of the control group (55,03±3,28 vs. 45,21±2,48%,
p<0,01) along with early discharge of amniotic fluid (44,95±1,39 vs. 38,70±1,46%, p<0,01). Suppression of IL-10 level, is observed at high levels of Anti-
Toxoplasma-IgG, as evidenced by the negative correlation between them (r=-0,27, p=0,004). However, Anti-HSV 1/2-IgG does not have a negative effect on
the level of Neopterin in infants. The relationship between Anti-CMV-IgG and IL-1 (r=0,75, p<0,001) indicates the stimulation of the inflammatory process in
premature infants and inhibition of IL-10 synthesis (r=-0,29, p=0,002 ).
Conclusions: A negative correlation between IL-10 level in infants and levels of Anti-Toxoplasma-IgG in mothers, similar relationship was detected regarding
Anti-HSV 1/2-IgG on level of TNF-α. Anti-CMV-IgG and IL-1 correlation analysis detected the stimulation of inflammatory process in premature infants and
inhibition of IL-10 synthesis.
Додано/оновлено в НРАТ
2026-06-13
