Реєстраційний номер
2125U009327, Матеріали видань та локальних репозитаріїв
Категорія
Текст
Назва роботи
Exploring the Effect of Subtotal Resection on Survival Outcome in Glioblastoma: A Case Study
Автор
Chaulagain Deepak
Smolanka Volodymyr
Smolanka Andriy
Havryliv Taras
Chaulagain Deepak
Smolanka Volodymyr
Smolanka Andriy
Havryliv Taras
Дата публікації
10-01-2025
Постачальник інформації
Ужгородський національний університет
Першоджерело
https://dspace.uzhnu.edu.ua/handle/lib/81223
Видання
Опис
Abstract. Glioblastoma characterized by aggressive nature and poor prognosis remains a challenging entity in
neuro-oncology. Standard treatment modalities, including maximal safe surgical resection followed by adjuvant
chemotherapy and radiotherapy, aim to prolong survival and alleviate symptoms. However, despite these interventions,
prognosis remains dismal, particularly in cases of subtotal resection. This case study delves into the effect of subtotal
resection on survival outcomes in glioblastoma patients. A 46-year-old male presented with symptoms of headache
and left-sided weakness, prompting admission and subsequent surgical intervention. Subtotal resection, achieving
approximately 95 % tumor removal, was performed. Following surgery, the patient underwent chemotherapy with
temozolomide (75 mg/m2) for six weeks, omitting radiotherapy. Remarkably, the patient experienced symptom
alleviation post-treatment and survived for six months. This case highlights the potential of subtotal resection in
managing glioblastoma, particularly in cases where complete excision is not feasible. Additionally, it underscores
the need for individualized treatment approaches and further research to optimize outcomes in glioblastoma patients
with less favorable prognoses.
Додано/оновлено в НРАТ
2026-06-13
