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Information × Registration Number 0124U001926, ( 0224U033423  ) R & D request Title Creation of modern calixarene regulators of biochemical processes for medicine and biotechnology. Chapter 3. Search, design and establishment of properties of new potentially bioactive calixarene derivatives aimed at therapeutically important protein targets. Head Vovk Andrii I., Доктор хімічних наук Registration Date 18-02-2024 Organization V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine popup.description1 The purpose of the work is to search, design and establish the properties of new potentially bioactive organic and elementoorganic derivatives of calix[4]arene, aimed at known proteins as targets for the treatment of type 2 diabetes, as well as for antitumor therapy. The project involves the in vitro and in silico study of new inhibitors of protein tyrosine phosphatases and some other enzymes that catalyze the hydrolysis of phosphate bonds, as well as inhibitors of glutathione-S-transferases. popup.nrat_date 2024-12-09 Close