Search academic texts

Information × Registration Number 0215U004981, 0115U004199 , R & D reports Title Development of novel preventive technologies in treatment of acute rheumatic diseases by inhibiting proinflammatory action of nuclear components of dying cells. popup.stage_title Head Bilyy Rostyslav Olexandrovych, Registration Date 23-12-2015 Organization Institute of cell biology, National Academy of Sciences of Ukraine popup.description2 Dynamics of formation of apoptotic membrane vesicles containing nuclear components and molecular composition of the vesicles was established. In addition, the estimated content of DNA and histones in vesicles were investigate, as well as  the dynamics of their formation. The release of nuclear components of the apoptotic cells through membrane vesicles was quantified and dynamics of membrane vesicles populations based to their sizes were determined. The effect of antihistone antibodies on phagocytosis of opsonised secondary necrotic cells was detected. Product Description popup.authors Думич Тетяна Ігорівна Шафранська Галина Іванівна popup.nrat_date 2020-04-02 Close