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Information × Registration Number 0224U001659, 0122U001801 , R & D reports Title Molecular design of heterocyclic compounds using multicomponent and tandem reactions for bioactivity screening and optoelectronics popup.stage_title Head Obushak Mykola D., д.х.н. Registration Date 26-01-2024 Organization Ivan Franko National University of Lviv popup.description2  A number of new multicomponent and tandem reactions have been developed, which make it possible to design practically useful substances by resource- and energy-saving methods. It is shown that 5-aryl-3-(2-furyl)-(2-methyl)acrylaldehydes are convenient reagents for the construction of hybrid heterocyclic structures, in particular with furo[2,3-f]isoindole and imidazo[2,1-b ][1,3]thiazol-3-one. A new multicomponent tandem [4+2] Ugy–Diels-Alder cycloaddition reaction was developed for the synthesis of furo[2,3-f]isoindoles. A new method of synthesis of phenanthridone derivatives is proposed. Methods of obtaining new hybrid structures of thiazole with 1,2,3-triazole and thiazolone derivatives were developed and compounds with antitumor activity were discovered. Methods of obtaining a number of new donor-acceptor conjugates have been developed, connected by π-spacers, and OLED devices with different emission colors have been created on their basis. Product Description popup.authors Horak Yuriy Lytvyn Roman Zinoviyovych popup.nrat_date 2024-01-26 Close