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Information × Registration Number 0124U003835, ( 0224U032926  0225U004278  ) R & D request Title Molecular design, synthesis and preclinical testing of new thiazole and thiazolidine derivatives with selective action on cells of myeloproliferative neoplasms Head Finiuk Nataliya S., Кандидат біологічних наук Registration Date 04-09-2024 Organization Institute of Cell Biology of the National Academy of Sciences of Ukraine popup.description1 The goal of the project is to create highly effective selective agents with targeted action for the treatment of myeloproliferative diseases with JAK2, CALR, and MPL gene mutations. For this purpose, the molecular design of new thiazole and 4-thiazolidinone derivatives will be developed, based on which compounds capable of selectively inhibiting malignant cells with JAK2, CALR, and MPL gene mutations will be synthesized. popup.nrat_date 2024-12-09 Close